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Experimentally induced cholangiohepatopathy by dosing sheep with fractionated extracts from Brachiaria decumbens. Cruz C, Driemeier D, Pires VS, Schenkel EP. Department of Veterinary Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil. Cholangiohepatopathy was induced in 5 lambs by oral administration of extracts from signal grass (Brachiaria decumbens) in Brazil. Grossly there were pale foci multifocally distributed throughout the hepatic parenchyma in 4 lambs. The microscopic changes, which were similar to those produced by other steroidal sapogenins-containing plants such as Tribulus terrestris and Panicum spp., included multifocal cholangitis, bile duct proliferation, and the presence of crystals in the biliary system. Send some email to Sharp Labs Inc. 
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