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Anabolic steroids are synthetic derivatives of the male hormone testosterone. The full name is androgenic (promoting masculine characteristics) anabolic (building) steroids (the class of drugs). These derivatives of testosterone promote the growth of skeletal muscle and increase lean body mass. Anabolic steroids were first abused nonmedically by elite athletes seeking to improve performance. Today, athletes and others use steroids to enhance performance and also to improve physical appearance. The major side effects of anabolic steroid use include liver tumors, jaundice, fluid retention, and high blood pressure; others are severe acne and trembling. Additional side effects include the following: For men - shrinking of the testicles, reduced sperm count, infertility, baldness, development of breasts. For women - growth of facial hair, changes in or cessation of the menstrual cycle, enlargement of the clitoris, deepened voice. NIDA-supported research shows that aggression and other psychiatric side effects may result from anabolic steroid abuse. Many users report feeling good about themselves while on steroids, but researchers report that steroid abuse can cause wild mood swings including manic-like symptoms leading to violent, even homicidal, episodes. Depression often is seen when the drugs are stopped and may contribute to steroid dependence. Researchers reported also that users may suffer from paranoid jealousy, extreme irritability, delusions, and impaired judgment stemming from feelings of invincibility. Steroids are taken orally or injected, and athletes and other abusers take them typically in cycles of weeks or months, rather than continuously, in patterns called cycling. Cycling involves taking multiple doses of steroids over a specific period of time, stopping for a period, and starting again. In addition, users frequently combine several different types of steroids to maximize their effectiveness while minimizing negative effects, a process known as stacking. People who inject steroids run the added risk of contracting or transmitting hepatitis or the virus (HIV) that leads to AIDS. Possession and distribution of anabolic steroids for nonmedical purposes are illegal under Federal law. In November 1990, steroids were added to Schedule III of the Federal Controlled Substances Act, which made the nonmedical possession of anabolic steroids a criminal act and greatly increased the penalties for steroid distribution. Possession of steroids is now punishable by up to 1 year in prison, and distribution can draw a sentence of up to 5 years and a fine of $250,000.
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